Affordable Generic Atypical Antipsychotics are here

Mental illness; Psychoses, Neuroses and Mood Disorders are a significant burden on Healthcare systems worldwide. Mental Disorders are more common than we think with a report from the World Health Organisation (WHO) in October 2014 stating that schizophrenia alone affects more than 21million people.

Antipsychotics

Antipsychotics

Mental illness is often seriously under diagnosed even in the most developed healthcare systems, but growing awareness and a decrease in the stigma often associated with it are leading to better diagnosis and outcomes.

Atypical (or second generation) Antipsychotics (AAPs) have broadly replaced typical antipsychotics as first line treatment for medical conditions that include:

Schizophrenia – Reduce positive symptoms
Bipolar Disorder – Manic Depressive disorder – successful management of acute mania and mixed episodes
Non-Psychotic Major depressive disorder – as adjunctive agents
Autistic Spectrum – behavioural disturbances associated with Autism.
Recent studies have shown short-term controlled evidence to support their use as augmenting agents in the treatment of refractory OCD with some patients
Data to suggest Olanzapine as a peripheral treatment for Anorexia Nervosa may decrease anxiety at meal times and increases weight gain

Major advantages of 2nd Generation Antipsychotics (AAPs) such as Risperidone, Olanzapine and Quetiapine over typical antipsychotics are:

Less likely to cause extrapyramidal symptoms – drug induced movement disorders including dystonia (continuous spasms) and akathisia (restlessness)
An absence of sustained Prolactin elevation

All antipsychotics (neuroleptics) work by antagonising Dopamine receptors (particularly D2) and to a lesser extent the serotonin receptors (particularly 5-HT2A) in the brain.

The “Fast-Off Theory” proposes that AAPs achieve such a comparatively low adverse effect profile than typical Antipsychotics by binding more loosely to the D2 receptors: only binding long enough to produce their therapeutic effects, but not long enough to produce extrapyramidal side effects or prolactin elevation.

Conclusion:
Because treatment with Antipsychotics can often be lifelong it is great news to the consumer that there are now affordable generics of equal quality and therapeutic value available.Affordable Generic Atypical Antipsychotics are here – Taj Dearob |Mental illness; Psychoses, Neuroses and Mood Disorders are a significant burden on Healthcare systems worldwide. Mental Disorders are more common than we think with a report from the World Health Organisation (WHO) in October 2014 stating that schizophrenia alone affects more than 21million people.
Affordable Generic Atypical Antipsychotics are here – Taj Dearob |Mental illness; Psychoses, Neuroses and Mood Disorders are a significant burden on Healthcare systems worldwide. Mental Disorders are more common than we think with a report from the World Health Organisation (WHO) in October 2014 stating that schizophrenia alone affects more than 21million people.