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Therapeutic Category



Losartan is an angiotensin II receptor blocker (ARB). It works by relaxing blood vessels. This helps to lower blood pressure.

UK Generic Name




Therapeutic Category



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Treating high blood pressure alone or with other medicines. It is used in certain patients to decrease the risk of stroke. It is used in certain patients to treat kidney problems caused by diabetes (diabetic nephropathy). It may also be used for other conditions as determined by your doctor.

Losartan is an angiotensin II receptor blocker (ARB). It works by relaxing blood vessels. This helps to lower blood pressure.

Do NOT use losartan if:

• you are allergic to any ingredient in losartan
• you are pregnant
• the patient is a child with severe kidney problems
• you are taking a medicine that contains aliskiren and you also have diabetes or kidney problems. Check with your doctor or pharmacist if you are not sure if a medicine you take contains aliskiren

Contact your doctor or health care provider right away if any of these apply to you.

Before using losartan:

Some medical conditions may interact with losartan. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are able to become pregnant
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness), including angioedema caused by treatment with an angiotensin-converting enzyme (ACE) inhibitor (eg, lisinopril)
• if you have a history of heart problems (eg, heart failure), blood vessel problems, blood flow problems, diabetes, or liver or kidney problems
• if you have a history of stroke or recent heart attack
• if you are dehydrated or have low blood volume
• if you have electrolyte problems (eg, high blood potassium levels, low blood sodium levels), vomiting or diarrhea, or are on a low-salt (sodium) diet
• if you are on dialysis

How to use losartan:

Use losartan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

An extra patient leaflet is available with losartan. Talk to your pharmacist if you have questions about this information.
Take losartan by mouth with or without food.
If you cannot swallow tablets, ask your doctor or pharmacist about preparing a suspension of losartan.
Take losartan on a regular schedule to get the most benefit from it. Taking losartan at the same time each day will help you remember to take it.
Continue to take losartan even if you feel well. Do not miss any doses.
If you miss a dose of losartan, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use losartan.

Possible side effects of losartan:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; diarrhea; dizziness; symptoms of upper respiratory tract infection (eg, cough, runny or stuffy nose, sneezing, sore throat); tiredness.

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